In fact, our series has the highest rate of patients with lymph node metastases and high Gleason score, but at the same time the lower rate of R1 patients, whereas the proportion of patients with pre-surgical PSA > 10 ng/ml is poorly comparable and that of patients with post-surgical PSA > 0.2 ng/ml is similar to that of randomized trials. Here, KLK3 is linked to metastatic malignant neoplasm in the lymph nodes.