As Fig. 3A showed, the initial exploration of the three databases demonstrated that AKR1B10 presented a significantly higher level of expression in tumor tissues compared to the normal liver tissues (P = 3.50E-11 for GSE14323, P = 8.17E-7 for GSE14520 and P = 6.98E-9 for GSE6764). This evidence concerns the gene AKR1B10 and neoplasm.