ZDHHC8 and epilepsy: Although it is not clear that ZDHHC8 participates in the chain of events leading to the precipitation and recurrence of seizures, our animal studies indicated that behavioral seizures seldom recurred in the rAAV-ZDHHC8-sh-treated animals but were higher in the rAAV-ZDHHC8-treated mice, whereas epilepsy developed normally in the control and rAAV-Empty-GFP-treated mice.