AKT1 and neoplasm: As predicted by our earlier studies, tumors from animals injected with the AKT/HCT 116 cells grew more rapidly and aggressively, as is evident from the higher tumor volume of AKT-6/HCT 116 and AKT-12/HCT 116 injected mice than pCMV/HCT 116 tumors (Fig. 6a).