We validated the prognostic significance of RASAL2 in TCGA (n = 520), Kaplan-Meier survival analysis also showed that copy number gain of RASAL2 and higher RASAL2 mRNA expression was correlated with aggressive disease-free survival (Fig. 2d) and overall survival in CRC patients (Fig. 2e). Here, RASAL2 is linked to colorectal carcinoma.