Our results also suggest that, by inhibiting overexpression of the NF-kB1 and NFKBia, the ORNs-d-M can impair influenza-induced overexpression of the cytokines, chemokines, ISGs, and pro-oxidation genes and inhibit influenza virus replication dependent on an active NF-kB signaling pathway [64,65]. This evidence concerns the gene NFKB1 and influenza.