CD8A and infection: In another model of infection, Tartz et al. showed that a detoxified CyaA protein carrying a CD8+ T cell epitope derived from the circumsporozoite protein (CSP) from Plasmodium berghei could protect mice from infection by this parasite, when used in a heterologous prime/boost vaccination protocol in conjunction with a live Salmonella vaccinal strain expressing the same CSP antigen [118].