Notably, neither 24 (Figure 3B and Figure S2A) nor 48 (Figure S2B and C) hours of co‐incubation of MA::Art v 1 VNP, Art v 1::GPI VNP, empty VNP (10 μg/mL each), or rArt v 1 protein (1 μg/mL) with bone marrow‐derived dendritic cells (BMDC) of TCR/DR1 allergy mice upregulated CD40, CD80, CD86, or MHC class II expression, when compared to medium. This evidence concerns the gene CD80 and allergic disease.