Antibodies against a variety of neural antigens such as amyloid ß proteins and peptides (1-42), tau protein, asialoganglioside GM1, S100B, glial fibrillary acidic protein (GFAP), rabaptin-5 (rab-5), adenosine triphosphate synthase (ATP-synthase), myelin basic protein (MBP), and many others known as autoantigens in Alzheimer's disease (AD) are detected in the sera or cerebrospinal fluids (CSF) of patients with AD [2, 8]. The gene discussed is MBP; the disease is Alzheimer disease.