However, elevated CDK18 mRNA expression (above median) was associated with reduced patient survival across the whole cohort (n = 1975, Log Rank -5.139, p = 0.02), which was also true for ER- tumours (n = 437, Log Rank –3.729, p = 0.05), but not for ER+ tumours (Figure 1C). The gene discussed is CDK18; the disease is neoplasm.