Stratification by MSI status (Table 1) showed that in microsatellite stable (MSS) stage III colon cancers (n=109) low expression of MACROD2 was associated with poor DFS (p=0.02; HR=2.0, 95% CI 1.1-3.7; Figure 2E). Here, MACROD2 is linked to malignant colon neoplasm.