THBD and coronary artery disorder: Thrombomodulin is a glycoprotein present on the surface of endothelial cells.13 It has a role in vasoprotection by converting procoagulant thrombin into an anticoagulant.6 Based on the results of this un-matched case-control study, we found a significant association between C1418T polymorphism and CAD i.e. the frequency CT and TT genotypes are more in cases as compared to controls considering both cases and controls were in Hardy-Weinberg equilibrium.