We also found that FX secreted to GBM cell supernatants decreased THP-1 cell M1 subtype marker (IL-1β, IL-12α, CXCL9, IL-12β, and CXCL10) expression, while increasing M2 subtype markers (LYVE1, MRC1, STAB1, and SerpinB2) expression. Here, IL1B is linked to glioblastoma.