FCGR2B and autoimmune disease: While FcγRIIb loss-of-function is associated with lupus (Siriboonrit et al., 2003; Tsuchiya and Kyogoku, 2005; Jakes et al., 2012), HP infection has been associated with other autoimmune diseases such as immune thrombocytopenic purpura and membranous nephropathy (Hasni et al., 2011).