The results of microarray analysis showed that lncRNAs HOTAIR, CCAT1, DNM3OS, HIF1A‐AS1, MEG3 and 7SK expressions were up‐regulated, and lncRNAs PCAT1, MIR31HG, BCAR4, RRP1B and H19 were down‐regulated within retinoblastoma tissues (Figure 1A). The gene discussed is HOTAIR; the disease is retinoblastoma.