Alternatively, lncRNA H19 inhibited progression of retinoblastoma cells via offsetting the action of miR‐17‐92 cluster,41 and lncRNA CCAT1 negatively regulated miR‐218‐5p to facilitate the proliferation and growth of SO‐RB50 and Y79 cell lines.13 HOTAIR, situated in chromosome 12 between HOXC11 and HOXC12, covered a length of 2.2 nt,14, 42 so it was also called as long intergenic non‐coding RNA (lincRNA). This evidence concerns the gene H19 and retinoblastoma.