Fig 3 shows representative images of immunohistochemical staining on epithelial cells. When the H-score yielded a value lower than 10, results were considered negative and were represented as not detectable (ND). Using the AR-NTD/AR-CTD ratio, we observed a wide distribution in epithelial nuclei of PCa samples, although it failed to reach statistical significance (P = 0.818) (Figure in S1 Fig). Here, AR is linked to posterior cortical atrophy.