By screening 162 probands with BrS or BrS combined with short QT syndrome (SQTS) (BrS+ SQTS), there were 7 newly identified mutations in CACNA1C, including p.E1115K, p.R1880Q, p.V2014I, p.D2130N, p.E1829_Q1833dup, p.C1873Y and p.E850del [102]. This evidence concerns the gene CACNA1C and Familial short QT syndrome.