Opposed to effects on CTSB and as expected based on our previous observations (Dhar et al., 2016, 2017), MTA1 negatively regulates E‐cad expression in primary tumor, a hallmark of EMT associated with metastasis (Figiel et al., 2017), indicating the impact of MTA1 in the process of EMT and cancer cell ability to migrate to distant sites. Here, CDH1 is linked to cancer.