Recently, inflammation-based index and scoring systems, such as the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), C-reactive protein (CRP)/albumin (Alb) ratio, Glasgow Prognostic Score (GPS), and modified GPS, have been reported as useful prognostic indicators in HCC [9–13]. This evidence concerns the gene CRP and hepatocellular carcinoma.