Both CD8 + CD57 + CD28- T cell count (110/mm3 (52–173) vs 57/mm3 (29–61); p = 0.034) and frequency (38.5% (3.6–76.8) vs 26.1 (2.1–46.9); p = 0.039) were higher in HD patients. The gene discussed is B3GAT1; the disease is Huntington disease.