This is in line with observations made by others, for example, (33) showed that after treating NIT-1 insulinoma cells with IFNγ, presentation of the high affinity JAK-1355–363 (SYFPEITHI) peptide by H-2Kb was increased from ~2,000 to ~15,000 copies per cell; whereas, the lower affinity IGRP206–214 peptide (VYLKTNVFK), barely detectable at 1 copy per cell in untreated cells, reached 25 copies per cell after IFNγ treatment. Here, IFNG is linked to pancreatic insulinoma.