MRC1 and retinitis pigmentosa 1: Recently, Cotter's laboratory and ours have reported that different kind of compounds (progesterone, sp2-iminosugar dodecylsulfoxide or chemical inhibitors of protein tyrosine phosphatase 1B) are able to act on microglial cells to reduce the proinflammatory milieu by decreasing TNF-α, IL-1β, and iNOS levels and stimulate the antiinflammatory phenotypes by increasing CD206/MRC1 and arginase-1 in mouse models of models of RP (rd10) or DR (db/db), respectively (Arroba et al., 2016a; Roche et al., 2016).