Following this approach, Zhao Y. et al. (2016) investigated a dual targeting strategy for ischemic stroke treatment, using liposomes containing a neuroprotectant (ZL006) with their surface decorated with a transferrin receptor-derived peptide ligand (T7) to improve the passage across the BBB and a stroke-homing peptide (SHp) to target the ischemic region. The gene discussed is TFRC; the disease is stroke disorder.