FoxM1 induction acts not only through modulation of mitotic fidelity and senescence pro-inflammatory phenotype, but also by improving the proliferative capacity of fitter (undamaged) cells in the elderly cell population that dilute, rather than totally clearing, the full-blown senescent cells, thereby coping with the detrimental but also beneficial (wound healing, tumor suppression) effects of senescence. Here, FOXM1 is linked to neoplasm.