Immunohistochemical staining revealed nuclear ARMC12 expression in 32/42 (76.2%) NB tissues, which was higher in tumor cases with poor differentiation (P = 0.013, Pearson chi-square test), higher mitosis karyorrhexis index (MKI, P = 0.006, Pearson chi-square test), or advanced INSS stages (P = 0.008, Pearson chi-square test, Supplementary Table 3). The gene discussed is ARMC12; the disease is neuroblastoma.