NDRG4 and colorectal carcinoma: The results demonstrated that SFRP2, SFRP1 and NDRG4 in CRC; VIM in AA; SFRP1, VIM and SFRP2 in TA; SFRP2 in HP; and SFRP1, SFRP2, NDRG4 and VIM in TP patients offer the most accurate detection in their corresponding categories (Fig 4).