N-myc downstream regulated gene 4 (NDRG4) could be also considered as a significant diagnostic marker gene in CRC (DOR: 24.37; 95%CI, 10.11–58.73) and Vimentin (VIM) in adenoma (DOR: 15.21; 95%CI, 2.72–85.10). The gene discussed is NDRG4; the disease is colorectal carcinoma.