TERT and thyroid cancer: The most common distance metastasis caused by thyroid cancer were osseous metastasis and pulmonary metastasis.[31] Five studies brought this clinicopathological feature into their studies[10,11,16,20,22] (heterogeneity: Tau = 1.42, Chi2 = 17.29, I2 = 78%, Z = 3.25, P < .01, random efforts model), and 4 of them[10,11,16,22] made a conclusion that TERT promoter mutations were relevant to it.