TERT and thyroid tumor: We collected data from 5 studies [11,17,19–21] (heterogeneity: Tau2 = 0.31,Chi2 = 9.16, I2 = 56%, Z = 0.57, P = 4.57, random efforts model), and 3 of them[19–21] tells that multifocal thyroid tumors are more likely to occur in TERT promoter mutation-positive patients (P < .05).