In the patient who had the longest survival, the Ki-67 labeling index was <10%, which indicates that, according to the current World Health Organization (WHO) classification system, the appropriate diagnosis was NET rather than NEC.[16] This correct distinction makes the longest survival time 23 months rather than 45 months, which is particularly disappointing.[25] Regarding the remaining 4 patients treated without surgical intervention, none survived more than one year. The gene discussed is MKI67; the disease is neuroendocrine carcinoma.