In the last experimental period examined (Day 7), the amount of myonecrosis, number of inflammatory cells, CD68+ (M1) and CD206+ (M2) macrophages as well as the expression of IL‐6, TNF‐α and TGF‐β mRNA were lower compared with previous periods (Day 2 and 4). Here, TGFB1 is linked to gas gangrene.