Here, the proinflammatory cytokines IL‐6 and TNF‐α mRNA were also highly expressed on Day 2, as described previously.1 Four days after injury, reductions were found in myonecrosis, the infiltration of inflammatory, cells and CD68+ (M1) macrophages as well as the expression of IL‐6 and TNF‐α mRNA. This evidence concerns the gene TNF and gas gangrene.