In order to compare the effect of RG7112 and AMG232 (Fig. 1a) in glioblastoma cell lines, we tested the sensitivity of previously known TP53 mutant cell lines (U373MG, LN18, and U251MG) and TP53 wild-type cell lines (A1207, DBTRG-05MG, and U87MG)24–26 to the drugs. Here, TP53 is linked to glioblastoma.