MLANA and neoplasm: In agreement with the IFN-γ release experiments, MART-1-specific CD8+ T cells generated through Ad5/3-MART-1 transduced or MART-126–35L peptide-pulsed MoDCs showed specific cytolytic activity against the HLA-A2+ MART-1+ MEL-AKR tumor cell line, but not the HLA-A2− MART-1+ MEL-JKO cell line (Figure 2c).