HNF1B and diabetes mellitus: In this study, we set out to characterise the epigenetic signature of HNF1B-associated disease and to determine if the signature differs depending on mutation classification: we profiled genome-wide patterns of DNA methylation in 20 individuals with an HNF1B intragenic mutation (HNF1Bmtn), 20 individuals with a 17q12 deletion encompassing HNF1B (17q12del) and 20 controls (ctrl) matched for age, gender and diabetes status.