Remarkably, circulating full-length ANGPTL8 concentrations were significantly elevated in the dyslipidemia group compared with the non-dyslipidemia group (506.18 [368.31–723.56] vs. 408.21 [294.52–511.41] pg/mL, P < 0.001) (Table 1). Here, ANGPTL8 is linked to metabolic syndrome.