In total, our study included 40 cases of DHL (25 with MYC and BCL2 rearrangements, 10 with MYC and BCL6 rearrangements, and 5 'triple-hit lymphomas' with MYC, BCL2 and BCL6 rearrangements) and 58 cases of DEL (non-DHL), including 51 cases of DLBCL, NOS (17 of Germinal Center B cell-like [GCB] origin, 34 of non-Germinal Center B cell-like [non-GCB] origin, by Hans criteria [16]) and 7 cases of HGBCL, NOS. This evidence concerns the gene BCL2 and lymphoma.