On admission, the median liver functional values were as follows: AST 459 U/L (167-1623 U/L); ALT 555 U/L (141-265 U/L); TB 22.9 mg/dL (6.21-44.2 mg/dL); INR 4.34 (1.7-10.7); creatinine 0.72 mg/dL (0.42-1.74 mg/dL); model for end-stage liver disease (MELD) score 34 (30-40); and factor V 25% (13-31%). The gene discussed is GPT; the disease is End Stage Liver Disease.