Cur attenuates ET-1 induction triggered by T. cruzi infection - Upon parasite infection (14 dpi), an elevated serum concentration of ET-1, an important contributor to vascular compromise that is characteristic of T. cruzi-mediated cardiomyopathy6,22, was demonstrated by ELISA in acute Chagas mice (Fig. 4A). This evidence concerns the gene EDN1 and parasitic infectious disease.