NEAT1 and heart failure: NEAT1 is the lncRNA that localizes to hundreds of genomic sites in cells, primarily over active genes.18 Some studies had found that NEAT1 functioned in multiple biological processes, such as altering the epigenetic landscape of target gene promoters, regulating cell proliferation and implicating in miRNA‐associated pathways.19, 20, 21 Heart failure always accompanied with myocardial fibroblasts proliferation.