CDKN2A and myocardial infarction: CHRF is able to directly bind to miR‐489 and regulate Myd88 expression and hypertrophy.9 This team also demonstrated that lncRNA ARF could suppress miR‐188‐3p expression and then affect ATG7 expression, leading to autophagic cell death and myocardial infarction (MI).10 What's more, Song et al have proposed a pipeline to decode the cardiac hypertrophy‐associated ceRNA crosstalks between lncRNAs and mRNAs.11 Thus, it is necessary to investigate the essential regulatory mechanisms of lncRNAs in heart failure based on ceRNA.