Overall, CD203c is a robust and valuable parameter to quantify the total (immature plus mature) basophil compartment in the PB and BM in healthy individuals and in patients with CML.14 However, although basophilia is of major prognostic impact in these patients, CD203c has not yet been tested as a prognostic marker in CML. The gene discussed is ENPP3; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.