For example, it has been described that CML stem cells display c‐MET, the receptor for HGF and that basophil‐derived HGF acts as an autocrine growth regulator on CML LSC in the malignant clone.58 Indeed, HGF is a well‐known regulator of early myeloid progenitor cells.80, 81, 82. This evidence concerns the gene HGF and chronic myelogenous leukemia, BCR-ABL1 positive.