The diagnostics is primarily directed towards systemic disorders, such as coagulopathies (responsible for young age stroke in up to 50%, specifically with such risk factors as elevated lipoprotein level, homocysteinemia, factor V Leiden trombophilia, protein C/S deficiency, or antiphospholipid syndrome) or cardiac diseases which are the cause of 10–30% of pediatric stroke [7, 12, 18]. This evidence concerns the gene F5 and antiphospholipid syndrome.