Nonetheless, these findings are consistent with Guiraud et al. who showed that there was no change in endothelial EVs (CD31+, CD62E+, and CD42b−) or platelet EVs (CD42b+) in 19 male coronary heart disease patients when measured up to 72 hr following either high-intensity interval or moderate-intensity cycling exercise [60]. This evidence concerns the gene PECAM1 and coronary artery disorder.