TP53 and neuroblastoma: The aims of this study were first to characterise neuroblastoma cell lines with respect to their sensitivity to X-irradiation and 177Lu-DOTATATE as well as their ability to activate p53 signalling following treatment with nutlin-3, topotecan or X-irradiation; and second to assess whether the combination treatment consisting of topotecan and nutlin-3 sensitised neuroblastoma cells to X-irradiation and 177Lu-DOTATATE treatment and the relationship with activation of p53 signalling.