Therefore, many studies have demonstrated that neuroinflammatory and sustained increases in various proinflammatory mediators including interleukin-6 (IL-6), interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α) in the CNS are closely related to the memory impairment primarily related to progress of AD pathogenesis [6, 7]. Here, IL6 is linked to Alzheimer disease.