COMT and schizophrenia: In male patients with schizophrenia, in the TRS group, COMT rs4818 (χ2 = 1.333; df = 1; p = 0.248) and COMT rs4680 (χ2 = 0.929; df = 1; p = 0.335) genotypes distributions did not deviate from HWE.