Total monocyte and lymphocyte numbers, as well as C-reactive protein (CRP) and tumor necrosis factor (TNF)-α, interleukin (IL)-6, IL-8 cytokine levels in the peripheral blood were unchanged between early course PD patients and controls (Student’s unpaired t-test, p-value > 0.05; Fig. 2). This evidence concerns the gene CRP and Parkinson disease.