EGFR and glioblastoma: To avoid RNA-interfered EGFR’s influence on Lycorine, the subsequent cell viability assay was conducted by treating GBM cells with Lycorine for 48 h of a comparably short time, before the time point of day 5 to refrain from EGFR’s long-term knockdown in decreasing cell growth, and the results were shown in Fig. 5g.