UGT1A1 and acute myeloid leukemia: We noticed that the predictive value of UGT1A1*28 and *6 polymorphisms on CR after Ara-C based induction therapy is modest in AML patients (CR rate 76.9% in carriers of the UGT1A1*28 and *6 alleles and 63.8% in UGT1A1*1/*1 for both loci), and the association of UGT1A1*28 alone with non-CR risk was nonsignificant after Bonferroni correction for two SNPs (significance set at P < 0.05/2 for 2 SNPs).