We identified a total of 1335 cases of HF hospitalization among users of saxagliptin (n = 49,214) compared to 2058 cases among matched GLP-1 agonists users (n = 49,214); and 6108 cases among sitagliptin users (n = 160,609) compared to 6239 among GLP-1 agonists matched users (n = 160,609). Here, GCG is linked to hydrops fetalis.