Multivariate analysis revealed that elevated ALT was associated with the highest likelihood of association with obesity (AOR: 4.146, 95% CI:1.878–9.154, p<0.001), followed by elevated creatinine level (AOR: AOR:3.504, 95% CI:1.351–9.008, p = 0.01), occurrence of chills and rigors (AOR:2.653, 95% CI: 1.286–5.474, p = 0.008), raised haematocrit (AOR: 1.953, 95% CI: 1.010–3.778, p = 0.047), body temperature (AOR:1.485, 95% CI: 1.080–2.042, p = 0.015) and systolic blood pressure (AOR:1.057, 95% CI:1.037–1.078, p<0.001). This evidence concerns the gene GPT and obesity due to melanocortin 4 receptor deficiency.