Thus, the reduced levels of PlGF and TAO-C and increased sFlt-1 and 8-epiPGF2α observed among AMA women in this study are reflections of an increased OS and abnormal placental angiogenesis culminating into stillbirth, low birth weight babies, low APGAR score and IUGR [12, 28]. The gene discussed is PGF; the disease is fetal growth restriction.