PTF1A and adenocarcinoma: Based on the genetic alterations common to both human pancreatic cancer and in the Ptf1a-Cre; LSL-KrasG12D mouse model, and based on the common progression through a precancerous PanIN phase that proceeds to prancreatic adenocarcinoma, it is commonly assumed that the Ptf1a-Cre; LSL-KrasG12D mouse strain is a good model for what is observed in the human clinical scenario.